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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

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perform basic research in molecular biology

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offer vital services to scientists in the member states

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scientists, students and visitors at all levels

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and development of technology

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new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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proteasome* AND author_name:"Zhu Y"

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EMDB [31]
EMPIAR [1]

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EMD-14201

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Proteasome-ZFAND5 Complex Z+A state

Release date: Feb. 8, 2023
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7qxn
Q-score: 0.319

To Be Published

Sample:

26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
26s protease regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
26s protease regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
26s protease regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
Proteasome-zfand5 complex z+a state (Complex from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
26s protease regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)

[Show more]

EMD-14202

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Proteasome-ZFAND5 Complex Z+B state

Release date: Feb. 8, 2023
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7qxp
Q-score: 0.336

To Be Published

Sample:

26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
Human proteasome zfand5 complex z+b state (Complex from Homo sapiens)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
26s protease regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
26s protease regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
26s protease regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
26s protease regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)

[Show more]

EMD-14203

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Proteasome-ZFAND5 Complex Z+C state

Release date: Feb. 8, 2023
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7qxu
Q-score: 0.233

To Be Published

Sample:

26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
26s protease regulatory subunit 7 (48 kDa, Protein from human)
Proteasome subunit beta type-1 (26 kDa, Protein from human)
Proteasome subunit beta type-3 (22 kDa, Protein from human)
Proteasome subunit alpha type-7 (27 kDa, Protein from human)
Proteasome subunit alpha type-3 (28 kDa, Protein from human)
Proteasome subunit beta type-7 (29 kDa, Protein from human)
26s proteasome regulatory subunit 8 (43 kDa, Protein from human)
Proteasome subunit alpha type-2 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
Proteasome subunit beta type-5 (28 kDa, Protein from human)
Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
Proteasome subunit beta type-6 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
26s protease regulatory subunit 6b (47 kDa, Protein from human)
Proteasome subunit beta type-2 (22 kDa, Protein from human)
26s protease regulatory subunit 6a (49 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
Human proteasome zfand5 complex z+c state (Complex from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
Proteasome subunit alpha type-6 (27 kDa, Protein from human)
26s proteasome complex subunit sem1 (8 kDa, Protein from human)
Proteasome subunit beta type-4 (29 kDa, Protein from human)
26s proteasome regulatory subunit 4 (48 kDa, Protein from human)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
Proteasome subunit alpha type-4 (29 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
Proteasome subunit alpha type-5 (26 kDa, Protein from human)
Magnesium ion (24 Da, Ligand)

[Show more]

EMD-14204

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Proteasome-ZFAND5 Complex Z+D state

Release date: Feb. 8, 2023
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7qxw
Q-score: 0.267

To Be Published

Sample:

26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
26s protease regulatory subunit 7 (48 kDa, Protein from human)
Proteasome subunit beta type-1 (26 kDa, Protein from human)
Proteasome subunit beta type-3 (22 kDa, Protein from human)
Proteasome subunit alpha type-7 (27 kDa, Protein from human)
Proteasome subunit alpha type-3 (28 kDa, Protein from human)
Proteasome subunit beta type-7 (29 kDa, Protein from human)
An1-type zinc finger protein 5 (23 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
Proteasome subunit beta type-5 (28 kDa, Protein from human)
26s proteasome regulatory subunit 4 (48 kDa, Protein from human)
Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
Proteasome subunit beta type-6 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from human)
26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
26s protease regulatory subunit 6b (47 kDa, Protein from human)
Proteasome subunit beta type-2 (22 kDa, Protein from human)
26s protease regulatory subunit 6a (49 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
Proteasome subunit alpha type-6 (27 kDa, Protein from human)
Human proteasome zfand5 complex z+d state (Complex from Homo sapiens)
26s proteasome complex subunit sem1 (8 kDa, Protein from human)
Proteasome subunit beta type-4 (29 kDa, Protein from human)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
Proteasome subunit alpha type-4 (29 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
Proteasome subunit alpha type-5 (26 kDa, Protein from human)
Magnesium ion (24 Da, Ligand)

[Show more]

EMD-14205

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Proteasome-ZFAND5 Complex Z+E state

Release date: Feb. 8, 2023
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7qxx
Q-score: 0.233

To Be Published

Sample:

26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
26s protease regulatory subunit 7 (48 kDa, Protein from human)
Proteasome subunit beta type-1 (26 kDa, Protein from human)
Proteasome subunit beta type-3 (22 kDa, Protein from human)
Proteasome subunit alpha type-7 (27 kDa, Protein from human)
Proteasome subunit alpha type-3 (28 kDa, Protein from human)
Proteasome subunit beta type-7 (29 kDa, Protein from human)
26s proteasome regulatory subunit 8 (43 kDa, Protein from human)
Human proteasome zfand5 complex z+b state (Complex from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
Proteasome subunit beta type-5 (28 kDa, Protein from human)
Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
Proteasome subunit beta type-6 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
26s protease regulatory subunit 6b (47 kDa, Protein from human)
Proteasome subunit beta type-2 (22 kDa, Protein from human)
26s protease regulatory subunit 6a (49 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
Proteasome subunit alpha type-6 (27 kDa, Protein from human)
26s proteasome complex subunit sem1 (8 kDa, Protein from human)
Proteasome subunit beta type-4 (29 kDa, Protein from human)
26s proteasome regulatory subunit 4 (48 kDa, Protein from human)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
Proteasome subunit alpha type-4 (29 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
Proteasome subunit alpha type-5 (26 kDa, Protein from human)
Magnesium ion (24 Da, Ligand)

[Show more]

EMD-14209

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Proteasome-ZFAND5 Complex Z-A state

Release date: Feb. 8, 2023
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7qy7
Q-score: 0.193

To Be Published

Sample:

26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
26s protease regulatory subunit 7 (48 kDa, Protein from human)
Proteasome subunit beta type-1 (26 kDa, Protein from human)
Proteasome subunit beta type-3 (22 kDa, Protein from human)
Proteasome subunit alpha type-7 (27 kDa, Protein from human)
Proteasome subunit alpha type-3 (28 kDa, Protein from human)
Proteasome subunit beta type-7 (29 kDa, Protein from human)
Proteasome subunit alpha type-2 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
Proteasome subunit beta type-5 (28 kDa, Protein from human)
Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
Proteasome subunit beta type-6 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
26s protease regulatory subunit 6b (47 kDa, Protein from human)
Proteasome subunit beta type-2 (22 kDa, Protein from human)
26s protease regulatory subunit 6a (49 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
Psmc5 isoform 15 (44 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
Human proteasome zfand5 complex z-a state (Complex from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
Proteasome subunit alpha type-6 (27 kDa, Protein from human)
26s proteasome complex subunit sem1 (8 kDa, Protein from human)
Proteasome subunit beta type-4 (29 kDa, Protein from human)
26s protease regulatory subunit 4 (49 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
Proteasome subunit alpha type-4 (29 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
Proteasome subunit alpha type-5 (26 kDa, Protein from human)

[Show more]

EMD-14210

Download Map 3D View

Proteasome-ZFAND5 Complex Z-B state

Release date: Feb. 8, 2023
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7qya
Q-score: 0.176

To Be Published

Sample:

26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
26s protease regulatory subunit 7 (48 kDa, Protein from human)
Proteasome subunit beta type-1 (26 kDa, Protein from human)
Proteasome subunit beta type-3 (22 kDa, Protein from human)
Proteasome subunit alpha type-7 (27 kDa, Protein from human)
Proteasome subunit alpha type-3 (28 kDa, Protein from human)
Proteasome subunit beta type-7 (29 kDa, Protein from human)
Proteasome subunit alpha type-2 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
Proteasome subunit beta type-5 (28 kDa, Protein from human)
Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
Proteasome subunit beta type-6 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from human)
26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
26s protease regulatory subunit 6b (47 kDa, Protein from human)
Proteasome subunit beta type-2 (22 kDa, Protein from human)
26s protease regulatory subunit 6a (49 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
Human proteasome zfand5 complex z-b state (Complex from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
Proteasome subunit alpha type-6 (27 kDa, Protein from human)
26s proteasome complex subunit sem1 (8 kDa, Protein from human)
Proteasome subunit beta type-4 (29 kDa, Protein from human)
26s protease regulatory subunit 4 (49 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
Proteasome subunit alpha type-4 (29 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
Proteasome subunit alpha type-5 (26 kDa, Protein from human)

[Show more]

EMD-14211

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Proteasome-ZFAND5 Complex Z-C state

Release date: Feb. 8, 2023
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7qyb
Q-score: 0.252

To Be Published

Sample:

26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
26s protease regulatory subunit 7 (48 kDa, Protein from human)
Proteasome subunit beta type-1 (26 kDa, Protein from human)
Proteasome subunit beta type-3 (22 kDa, Protein from human)
Proteasome subunit alpha type-7 (27 kDa, Protein from human)
Human proteasome zfand5 complex z-c state (Complex from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from human)
Proteasome subunit beta type-7 (29 kDa, Protein from human)
Proteasome subunit alpha type-2 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
Proteasome subunit beta type-5 (28 kDa, Protein from human)
Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
Proteasome subunit beta type-6 (25 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from human)
26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
26s protease regulatory subunit 6b (47 kDa, Protein from human)
Proteasome subunit beta type-2 (22 kDa, Protein from human)
26s protease regulatory subunit 6a (49 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
Proteasome subunit alpha type-6 (27 kDa, Protein from human)
26s proteasome complex subunit sem1 (8 kDa, Protein from human)
Proteasome subunit beta type-4 (29 kDa, Protein from human)
26s protease regulatory subunit 4 (49 kDa, Protein from human)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
Proteasome subunit alpha type-4 (29 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
Proteasome subunit alpha type-5 (26 kDa, Protein from human)
Magnesium ion (24 Da, Ligand)

[Show more]

EMD-9216

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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

Release date: Dec. 5, 2018
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6msb
Q-score: 0.389

Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y

Nature (2019) 565 pp. 49-55 [ Pubmed: 30479383 DOI: doi:10.1038/s41586-018-0736-4 ]

Sample:

Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (61 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
Ubiquitin (8 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
Human 26s proteasome (Complex from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Magnesium ion (24 Da, Ligand)

[Show more]

EMD-9217

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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

Release date: Dec. 5, 2018
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6msd
Q-score: 0.365

Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y

Nature (2019) 565 pp. 49-55 [ Pubmed: 30479383 DOI: doi:10.1038/s41586-018-0736-4 ]

Sample:

Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (61 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
Ubiquitin (8 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
Human 26s proteasome (Complex from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Magnesium ion (24 Da, Ligand)

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EMDB [31]
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